Suwen Su,

Professor, Supervisor of Doctorate Candidates, Supervisor of Master's Candidates

Hebei Province Key Laboratory of Innovative Drug Research and Evaluation, Department of Pharmacology,

Hebei Medical University. 

050017, Shijiazhuang, Hebei, CHINA

E-mail: suswmk@hebmu.edu.cn / suswmk@163.com

Education and Training

B.S., 1988.09-1993.06 Hebei Medical University.

M.D., 1994.09-1997.06 Hebei Medical University. 

Ph.D., 2000.09-2003.06, Hebei Medical University.

Postdoctoral Research Fellow, 2004.10-2006.09, Department of Pharmacology, Osaka University, Japan.

Professor, 2018-now, Department of Pharmacology, Hebei Medical University.

Research interests/Specialties: Drug Pharmacology and toxicology

Research Description:

1.The cytological basis and molecular mechanism of drug induced cardiomyopathy.

2.The prevention and treatment of drug induced cardiomyopathy.

Selected Publication:

1.X Wang, Q Jia, Y Yu, H Wang, H Guo, X Ma, Ch Liu, X Chen, Q Miao, B Guan, S Su*,H Wei*, and Ch Wang*. Inhibition of the I Na/K and the activation of peak I Na contribute to the arrhythmogenic effects of aconitine and mesaconitine in guinea pigs，Acta Pharmacologica Sinica (2020) 0:1–12; https://doi.org/10.1038/ s41401-020-0467-6.

2.Chen X, Guo H, Li Q, Zhang Y, Liu H, Zhang X, Xie K, ZHU Z, Miao Q, Su S*. The protective effects of Berberine on Aconite-induced myocardial injury and the Mechanisms. Mol Med Rep. 2018; 18(5):4468-4476.

3.Xiong C, Wu Y, Zhang Y, Wu Z, Zhang L, Jiang P, Guo H, Xie K, Su S*. Protective effect of berberine on acute cardiomyopathy related to doxorubicin-treatment. Oncol Lett. 2018; 15(4), 5721-9. 

4.Wu J, Wang X, Chung YY, Koh CH, Liu Z, Guo H, Yuan Q, Wang C, Su S*, Wei H*. L-Type Calcium Channel Inhibition Contributes to the Proarrhythmic Effects of Aconitine in Human Cardiomyocytes. PLoS One. 2017; 12(1): e0168435. 

5.Chen X, Zhang Y, Zhu Zh, Liu H, Guo H, Xiong Ch, Xie K, Zhang X, Su W*. The protective effect of berberine on doxorubicin-induced acute hepatorenal toxicity in rats. Mol Med Rep. 2016; 13(5): 3953-60. 

6.Jiang YF, Chen XY, Ding T, Wang XF, Zhu ZN*, Su SW*. Comparative Efficacy and Safety of OADs in Management of GDM: Network Meta-analysis of Randomized Controlled Trials. J Clin Endocrinol Metab. 2015; 100(5): 2071-80.

7.Wang LF1, Su SW1, Wang L, Zhang GQ, Zhang R, Niu YJ, Guo YS, Li CY, Jiang WB, Liu Y, Guo HC. Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes. Am J Transl Res. 2015; 7(10): 1724-35. 

8.Chen PP, Li CY, Han Y, Chen XY, Liu HL, Du YM, Su SW*, Zhang YJ*.  N-[4-(4,6-Dimethyl-2-pyrimidinyloxy)-3-methylphenyl]-N'-[2-(dimethylamino)] benzoylurea induces cell-cycle arrest and apoptosis in human cancer cells. Anticancer Drugs. 2015; 26(6): 620-31. 

9.Su S1, Li Q1, Liu Y, Xiong C, Li J, Zhang R, Niu Y, Zhao L, Wang Y, Guo H. Sesamin ameliorates doxorubicin-induced cardiotoxicity: Involvement of Sirt1 and Mn-SOD pathway. Toxicol Lett. 2014; 224(2): 257–63. 

10.Liu H, Chen X, Han Y, Li C, Chen P, Su S, Zhang Y, Pan Z. Rho kinaseinhibition by fasudil suppresses lipopolysaccharide-induced apoptosis of rat pulmonary microvascular endothelial cells via JNK and p38 MAPK pathway. Biomed Pharmacother. 2014 ;68(3):267-75.

11.何林峰，王可欣，雷蕾，张永健，苏素文*. 阿霉素减轻坐骨神经慢性缩窄性损伤大鼠的神经病理性疼痛及其机制. 中国药理学通报；2018；34(1)：33-8.